BCHM - Clinical Trial Calculation Based on BCHM Design
Users can estimate the treatment effect for multiple
subgroups basket trials based on the Bayesian Cluster
Hierarchical Model (BCHM). In this model, a Bayesian
non-parametric method is applied to dynamically calculate the
number of clusters by conducting the multiple cluster
classification based on subgroup outcomes. Hierarchical model
is used to compute the posterior probability of treatment
effect with the borrowing strength determined by the Bayesian
non-parametric clustering and the similarities between
subgroups. To use this package, 'JAGS' software and 'rjags'
package are required, and users need to pre-install them.
